SPICA 2022

18th International Symposium on Preparative and Industrial Chromatography and Allied Techniques

 Lisbon, Portugal    October 11-14, 2022

Keynote Lectures

Measurement of Separation Materials to Enable Mechanistic Modelling and Rational Design (KL01)

Prof. Dan BRACEWELL
Prof. Dan BRACEWELL
UNIVERSITY COLLEGE LONDON, London, United Kingdom
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Proteins at Chromatographic Surfaces – Competitive Binding and On-column Aggregate Formation on Monomodal and Multimodal Anion Exchangers (KL02)

Prof. Giorgio CARTA
Prof. Giorgio CARTA
UNIVERSITY OF VIRGINIA, Charlottesville, United States
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Process Scale MCSGP Purification of large Synthetic Molecules (KL03)

Dr Ralf EISENHUTH
Dr Ralf EISENHUTH
BACHEM, Bubendorf, Switzerland
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The Evolution of Chromatographic Processes for Small Molecules Between Research and Production of APIs (KL04)

Dr Gunnar GARKE
Dr Gunnar GARKE
BAYER AG, Wuppertal, Germany
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Automation and Digitalization in the Manufacturing of Therapeutic Proteins (KL06)

Prof. Massimo MORBIDELLI
Prof. Massimo MORBIDELLI
POLITECNICO MILANO, Milano, Italy
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Cyclic Adsorption Processes. What else? (KL07)

Prof. Alirio RODRIGUES
Prof. Alirio RODRIGUES
UNIVERSITY OF PORTO, Porto, Portugal
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What is the Right Level of Purity? Benefits of Overpurifying and Underpurifying in Chromatography (KL08)

Prof. Tuomo SAINIO
Prof. Tuomo SAINIO
LAPPEENRANTA UNIVERSITY OF TECHNOLOGY, Lappeenranta, Finland
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Invited Lectures

The Thar Process Journey Regarding Green Chemistry Application Using Supercritical Carbon Dioxide (IL10)

Dr Lalit CHORDIA
Dr Lalit CHORDIA
THAR PROCESS INC., Pittsburgh, United States
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Protein Purification Using Magnetic Adsorbents and Magnetic Separation - a Robust Alternative to Conventional Chromatography? (IL02)

Prof. Mathias FRANZREB
Prof. Mathias FRANZREB
KARLSRUHE INSTITUTE OF TECHNOLOGY, Karlsruhe, Germany
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Exploring Enhanced Selectivity of Mixed Mode Cation Exchange Resins in Bispecific and Complex Immunoglobulin Purification (IL08)

Mr Wolfgang KOEHNLEIN
Mr Wolfgang KOEHNLEIN
F. HOFFMANN-LA ROCHE, Penzberg, Germany
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Large Scale SFC to Enable Delivery of Candidate Drugs; Cost Savings, Sustainability and Fundamental Learnings (IL04)

Dr Hanna LEEK
Dr Hanna LEEK
ASTRAZENECA R&D, Mölndal, Sweden
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Models in the SMB and SMBR Process Development (IL01)

Dr Damien LEINEKUGEL LE COCQ
Dr Damien LEINEKUGEL LE COCQ
IFP ENERGIES NOUVELLES, Solaize, France
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Strategies and Emerging Technologies for Downstream Purification (IL06)

Dr Gunnar MALMQUIST
Dr Gunnar MALMQUIST
CYTIVA, Uppsala, Sweden
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Making Affinity Chromatography an Integral Part of Vaccine Development and Manufacturing (IL03)

Dr Mikkel NISSUM
Dr Mikkel NISSUM
GSK, Siena, Italy
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Chromatography in Colour – Application of Processes Chromatography to the Efficient Recycling of Critical Metals (IL07)

Dr Paul O'SHAUGHNESSY
Dr Paul O'SHAUGHNESSY
JOHNSON MATTHEY, Oxfordshire, United Kingdom
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Progress and Trends of Virus Based Biopharmaceuticals Purification (IL11)

Prof. Cristina PEIXOTO
Prof. Cristina PEIXOTO
IBET, Oeiras, Portugal
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The Role of CO2 Separation (SFC) in the Eco-Sustainable Production of APIs and Hemp Ingredients (IL09)

Dr Gerard ROSSE
Dr Gerard ROSSE
PIC SOLUTION, San Diego, United States
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Preparative Separation by Chromatography from Laboratory to Industrial Scale in a Pharmaceutical Environment Applied to Small Molecules (IL05)

Dr Antoni SEVERINO
Dr Antoni SEVERINO
UCB, Braine-l'Alleud, Belgium
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Oral Communications

Coupling Preferential Precipitation and IEX for Reducing Acidic Variant Content in Monoclonal Antibody Pools (OC04)

Prof. Dorota ANTOS
Prof. Dorota ANTOS
RZESZOW UNIVERSITY OF TECHNOLOGY, Rzeszow, Poland
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Fixed-Bed and Simulated Moving Bed Chromatography Using Achiral and Chiral Adsorbents for the Complete Preparative Separation of a Quaternary Mixture (OC07)

Mr Rami ARAFAH
Mr Rami ARAFAH
POLYTECHNIC INSTITUTE OF BRAGANÇA, Braganca, Portugal
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Industral Application of Supercritical Fluid Simulated Moving Bed in the Separation of N-3 Pufa from Fish Oil (OC17)

Ms Xiaoqing BAO
Ms Xiaoqing BAO
JOPE TECHNOLOGY CO., LTD , Kaohsiung, Taiwan
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Hybrid Models for the Simulation and Prediction of Chromatographic Processes (OC12)

Dr Alessandro BUTTE
Dr Alessandro BUTTE
DATAHOW, Zurich, Switzerland
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Simulated Moving Bed Chromatography - Mass Spectrometry (SMB-MS): Continuous On-Line Sample Preparation for Process Analytical Technology (OC14)

Ms Juliane DIEHM
Ms Juliane DIEHM
KARLSRUHE INSTITUTE OF TECHNOLOGY, Karlsruhe, Germany
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High-Throughput Analytical and Purification Capabilities at Janssen Research and Development, Toledo (OC08)

Dr Alberto FONTANA
Dr Alberto FONTANA
JANSSEN, Toledo, Spain
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Study of Liquid-Liquid Chromatography Operation in the Nonlinear Range of the Partition Equilibria (OC19)

Mrs Melanie GERIGK
Mrs Melanie GERIGK
TECHNICAL UNIVERSITY OF MUNICH, Freising, Germany
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Process Stabilization by Online Monitoring of a Mini-Plant Coupling Enantioselective SMB Chromatography and Enzymatic Racemization (OC18)

Ms Isabel HARRIEHAUSEN
Ms Isabel HARRIEHAUSEN
MAX-PLANCK-INSTITUTE, Magdeburg, Germany
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New Approaches in Preparative Chromatography for Lipid Nanoparticle (LNP) Building Blocks (OC10)

Dr Markus JUZA
Dr Markus JUZA
CORDEN PHARMA SWITZERLAND, Liestal, Switzerland
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Development of Preparative Chromatographic Processes for the Classification of Nanoparticles (OC01)

Prof. Malte KASPEREIT
Prof. Malte KASPEREIT
FRIEDRICH-ALEXANDER-UNIVERSITÄT ERLANGEN-NÜRNBERG, Erlangen, Germany
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Continuous Size Fractionation of Nanoparticles for Biomedical Purposes Using Magnetic Field Controlled SMB (OC13)

Ms Laura KUGER
Ms Laura KUGER
KARLSRUHE INSTITUTE OF TECHNOLOGY (KIT), Eggenstein-Leopoldshafen, Germany
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Short-Cut Design of Four-Zone Simulated Moving Bed Chromatography for Multi-Component Systems: Langmuir-Type Isotherms (OC15)

Dr Ju Weon LEE
Dr Ju Weon LEE
OTTO VON GUERICKE UNIVERSITY, Magdeburg, Germany
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Design and Operation of an Integrated Continuous Downstream Process for Acid-Sensitive Mabs Based on a Calcium-Dependent Protein a Ligand (OC21)

Prof. Bernt NILSSON
Prof. Bernt NILSSON
LUND UNIVERSITY, Lund, Sweden

Advanced Gradient SMBC Applied to Antibody Purification (OC20)

Mr Masahiro OGINO
Mr Masahiro OGINO
ORGANO CORPORATION, SAGAMIHARA-shi, Japan
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Protein Separation by Simulated Moving Bed (OC22)

Ms Albertina RIOS
Ms Albertina RIOS
UNIVERSITY OF PORTO, Porto, Portugal
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New Purification Strategy of Polyether Block Copolymers by Means of Simulated Moving Bed Size Exclusion Chromatography (OC09)

Dr Pedro SÁ GOMES
Dr Pedro SÁ GOMES
BASF SE, Ludwigshafen am Rhein, Germany
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Integration of Chromatography and Allied Separation Technologies Towards Autonomous Continuous MRNA Production (OC05)

Dr Axel SCHMIDT
Dr Axel SCHMIDT
INSTITUT FÜR THERMISCHE VERFAHRENSTECHNIK, TUC, Clausthal-Zellerfeld, Germany
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Intensified Purification of Monoclonal Antibodies with Double Flow-Through Membrane Chromatography (OC03)

Mr Fabian SCHMITZ
Mr Fabian SCHMITZ
SARTORIUS STEDIM BIOTECH GMBH, Göttingen, Germany
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Continuous Purification of Virus-Based Biologics Using Periodic Counter-Current Chromatography (OC06)

Dr Ricardo SILVA
Dr Ricardo SILVA
IBET, Oeiras, Portugal
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Robustness Analysis by Predictive Distribution for Various Operating Configurations for Simulated Moving Bed Chromatography (OC16)

Mr Kensuke SUZUKI
Mr Kensuke SUZUKI
NAGOYA UNIVERSITY, Nagoya, Japan
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Optimizing AAV Full/Empty Separation Using Mechanistic Modeling (OC02)

Dr Tatjana TRUNZER
Dr Tatjana TRUNZER
CYTIVA, Karlsruhe, Germany
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General Bio-Chromatographic Digital Twin in Quality-By-Design Based Process Design and Machine-Learning Based Process Control (OC11)

Mr Florian VETTER
Mr Florian VETTER
TU CLAUSTHAL, Clausthal-Zellerfeld, Germany
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